Why Does Water Make My Acid Reflux Worse

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  • By Joe Dangor
March 27, 2017

ROCHESTER, Minn. – Researchers at Mayo Clinic have found patients who use gastric suppression medications are at a higher risk for recurrent Clostridium difficile (C-diff) infection. C-diff is a bacterium that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon. The study is published in JAMA Internal Medicine.

"" says Sahil Khanna, M.B.B.S., a gastroenterologist at Mayo Clinic and senior author of the study.

Dr. Khanna says gastric suppression medications studied include proton pump inhibitors, such as omeprazole, and histamine 2 blockers, such as ranitidine, which are commonly prescribed and consumed over-the-counter medications for gastroesophageal reflux disease, peptic ulcer disease or dyspepsia.

Why Does Water Make My Acid Reflux Worse 7 Natural GERD (👍 Holiday) | Why Does Water Make My Acid Reflux Worse Diet Changes Forhow to Why Does Water Make My Acid Reflux Worse for In a systematic review and meta-analysis of 16 studies with 7,703 patients with C-diff, 1,525 developed recurrent C-diff. The rate of recurrent C-diff in patients with the 1 last update 08 Jul 2020 gastric suppression was 22.1 percent, compared to 17.3 percent in patients without gastric acid suppression.In a systematic review and meta-analysis of 16 studies with 7,703 patients with C-diff, 1,525 developed recurrent C-diff. The rate of recurrent C-diff in patients with gastric suppression was 22.1 percent, compared to 17.3 percent in patients without gastric acid suppression.

Dr. Khanna urges caution in interpreting these findings due to variables not considered in the study, such as the underlying reason why the gastric acid suppressant was needed. However, he says the findings suggest that patients with C-diff who receive gastric acid suppressants may be at increased risk of C-diff recurrence. "" Dr. Khanna says.

Co-authors are:

  • Raseen Tariq, M.B.B.S., Mayo Clinic
  • Darrel Pardi, M.D., Mayo Clinic
  • Siddharth Singh, M.B.B.S., University of California San Diego
  • Arjun Gupta, M.B.B.S., University of Texas South Western

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About Mayo Clinic
Mayo Clinic is a nonprofit organization committed to clinical practice, education and research, providing expert, whole-person care to everyone who needs healing. For more information, visit mayoclinic.org/about-mayo-clinic or newsnetwork.mayoclinic.org.

MEDIA CONTACT
Joe Dangor, Mayo Clinic Public Affairs, 507-284-5005,
[email protected]

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