Irritation In Chest After Eating

🔥+ Irritation In Chest After Eating 08 Jul 2020 What causes GERD? How does acid get from the stomach to the esophagus? Normally, a muscle called the lower esophageal sphincter (LES) ...

Irritation In Chest After Eating Gastroesophageal reflux disease (GERD) is a chronic condition in which retrograde flow of stomach contents into the esophagus causes irritation to the ...

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Gut Liver. 2011 Sep; 5(3): 298–301. Gut Liver. 2011 Sep; 5(3): 298–301.
Published for 1 last update 08 Jul 2020 online 2011 Aug 18. Published online 2011 Aug 18. doi: 10.5009/gnl.2011.5.3.298
PMCID: PMC3166669
PMID: 21927657

Fatemeh Farahmand

*Division of Pediatric Gastroenterology, Pediatrics Center of Excellence, Children''s Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Find articles by Mehri Najafi

Pedram Ataee

*Division of Pediatric Gastroenterology, Pediatrics Center of Excellence, Children''s Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Find articles by Vajiheh Modarresi

Turan Shahraki

Division of Pediatric Gastroenterology, Zahedan University of Medical Sciences, Zahedan, Iran.

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Irritation In Chest After Eating Treatment (🔥 List Of) | Irritation In Chest After Eating Diseasehow to Irritation In Chest After Eating for Nima Rezaei

Molecular Immunology Research Center and Department of Immunology, Tehran University of Medical Sciences School of Medicine, Tehran, Iran.

§Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children''s Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Division of Pediatric Gastroenterology, Zahedan University of Medical Sciences, Zahedan, Iran.
Molecular Immunology Research Center and Department of Immunology, Tehran University of Medical Sciences School of Medicine, Tehran, Iran.
§Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children''s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Tel: +98-918-371-3076, [email protected]_maredep
Received 2010 Jul 11; Accepted 2011 Jan 20.
Copyright © 2011 The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, the Korean Association for the Study of Intestinal Diseases, Korean Association for the Study of the Liver and Korean Society of Pancreatobiliary Diseases
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Abstract

Background/Aims

Gastroesophageal reflux disease (GERD) and cow''s milk from the diet was started for the patients who did not respond to the omeprazole treatment.

Results

Seventy-two cases presented with gastrointestinal signs and symptoms, whereas the remaining nine cases presented with respiratory complaints. After the initial treatment with omeprazole, two thirds of the cases (54 patients, 66.7%) responded well, and all of their symptoms were resolved. Cow''s milk from the diet.

Conclusions

A diagnosis of CMA was considered in one third of the pediatric cases with signs and symptoms of GERD. This finding shows that CMA can mimic or aggravate all signs and symptoms of severe GERD during infancy.

Keywords: Cow''s esophagus, and pulmonary disease.3,4

GERD is a multifactorial disease that frequently manifests during early infancy, and has a great tendency for spontaneous improvement during the first years of life, which might be as a result of feeding habits alteration as well as improved function of the lower esophageal sphincter (LES).1,5,6 Increased frequency of reflux in infants younger than age 4 months could suggest developmental immaturity of the LES,7,8 which seem to be the most common cause of gastroesophageal reflux in children.9-12

Association between GERD and cow''s Medical Center (Pediatrics Center of Excellence in Tehran, Iran) with signs and symptoms of GERD during 2006-2007, were enrolled in this study. There was no history of any previous underlying disease for the participants. Patients with associated diseases such as neurodevelopmental disorders, esophageal atresia and anatomical malformations were excluded from the study. The diagnosis of GERD was made based on clinical symptoms considering the medical history of patients and physical examination. Several questions regarding vomiting or regurgitation, crying, weight gain, respiration problems, cyanosis, apnea, pneumonia, bronchitis, chronic coughing, hiccups, and diarrhea were asked from the parents of patients.19 Barium swallow was also performed in some patients with intractable vomiting to evaluate esophageal stricture, hiatal hernia and/or intestinal obstruction.

All patients were treated with omeprazole 2 mg/kg/day divided in two doses for 4 weeks. The effect of omeprazole on GERD was assessed 4 weeks after treatment. For the patients who did not respond to this treatment, a trial of cow''s milk elimination was assessed after this 4-week period. Patients who respond to this elimination diet (including omitting cow''s milk allergy (CMA) and gastroesophageal reflux disease (GERD).

After initial treatment with omeprazole, 54 out of 81 patient (66.67%) responded well to this treatment; all of their symptoms were resolved. These patients were diagnosed as GERD.

Irritation In Chest After Eating Foods To Avoid (⭐️ Heartburn) | Irritation In Chest After Eating Breakfast Forhow to Irritation In Chest After Eating for The remaining 27 patients (33.33%) underwent an elimination diet of cow''s milk from diet; thus the diagnosis of CMA was considered for for 1 last update 08 Jul 2020 these patients.The remaining 27 patients (33.33%) underwent an elimination diet of cow''s milk from diet; thus the diagnosis of CMA was considered for these patients.

Among these 27 patients (15 male and 12 female) with CMA, 21 cases (77.78%) had gastrointestinal signs and symptoms, whereas 6 (22.22%) had respiratory symptoms. There was positive family history of allergy in at least one parent of 12 individuals (44.44%). The age distribution of patients with CMA in the 1 last update 08 Jul 2020 this study is summarized in Fig. 1.Among these 27 patients (15 male and 12 female) with CMA, 21 cases (77.78%) had gastrointestinal signs and symptoms, whereas 6 (22.22%) had respiratory symptoms. There was positive family history of allergy in at least one parent of 12 individuals (44.44%). The age distribution of patients with CMA in this study is summarized in Fig. 1.

DISCUSSION

GERD is a disease that commonly occurs during the first year of life; some forms of severe GERD have been shown to be associated with CMA.20,21 The pathogenesis of GERD is multifactorial and complex, involving the frequency of reflux, gastric acidity, gastric emptying, esophageal clearing mechanisms, the esophageal mucosal barrier, visceral hypersensitivity, and airway responsiveness.

In the present study, the CMA was diagnosed in one third of patients with sign and symptoms of GERD. A substantial part of these patients for 1 last update 08 Jul 2020 had family history of allergy or atopy. Although respiratory symptoms are expected to be seen in severe GERD, 6 out of 9 cases with respiratory symptoms were diagnosed as CMA. This finding shows that CMA can mimic all signs and symptoms of severe GERD.In the present study, the CMA was diagnosed in one third of patients with sign and symptoms of GERD. A substantial part of these patients had family history of allergy or atopy. Although respiratory symptoms are expected to be seen in severe GERD, 6 out of 9 cases with respiratory symptoms were diagnosed as CMA. This finding shows that CMA can mimic all signs and symptoms of severe GERD.

The prevalence of food hypersensitivities in childhood and infancy is estimated about 7-8%.22 CMA is the most common one with prevalence of 2-3% in the infants.23,24 CMA can involve several organs, particularly skin and gastrointestinal tract. All parts of gastrointestinal lumen, including the esophagus, stomach, small intestine, colon and rectum, may be involved in CMA.20,21 It should be noted that in this study the trial of cow''s milk protein either in formula fed infants or breast fed infants mother has been considered as an diagnostic strategy for infants suspected to having food allergy, followed by either an open challenge or a double-blind, placebo-controlled food challenge (DBPCFC) to confirm or exclude a food allergy. However, DBPCFC should be conducted in adults and in children older than 3 years.20,21,23

It should be noted that there are some differences between primary GERD or secondary GERD due to CMA. Although it is not expected that the patients with CMA respond to omeprazole and diet elimination is necessary for treatment, a 24-hour esophageal pH monitoring could be recommended to determine the etiology of disease.24

Irritation In Chest After Eating Breakfast For (🔥 Acid Reflux Symptoms) | Irritation In Chest After Eating Home Remedieshow to Irritation In Chest After Eating for Although the gold standard therapy of GERD is proton pump inhibitors and H2 receptor blockers, the diagnostic strategy in infants who are suspected of having food allergy should involve 2-4 weeks elimination diet. It should be noted that adherence to a diet without proper guidance may have a negative effect on growth and development.25-27 It is important to diagnose CMA to avoid unnecessary elimination diets. The treatment of gastrointestinal manifestations of CMA relies on avoidance of cow''s milk product in the patients with diagnosis of refractory GERD resolved the problems. It seems that cow''s milk protein allergy and intolerance in infancy: some clinical, epidemiological and immunological aspects. Pediatr Allergy Immunol. 1994;5(5 Suppl):1–36. [PubMed] [Google Scholar]

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Articles from Gut and Liver are provided here courtesy of The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association for the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, the Korean Society of Pancreatobiliary Disease, and the Korean Society of Gastrointestinal Cancer

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